Colt Python S.A.A. Weapon

Begin a normal difficulty game and go to the courtyard in front of the R.C.P.D., then go down the stairs. Brad Vickers from RE will be waiting for you. No, he's not going to give you the gun, but he WILL give you trouble if you try to face him with the few bullets you have left from your run through the City. Head into the Police Station and pick up more ammo and perhaps a stronger weapon before going to meet him. If you manage to fell him, you will get the Secret Key. Take this key to the Dark Room save area and use it to open the lockers to the left of the door. Inside is the Colt Python S.A.A., which is almost more powerful than the magnum. It only carries six shots, but it's great for the last battle against William G-III and G-IV. An alternate costume is also in the locker, if you like that kind of thing. Oh, and one more detail. If this doesn't work, in that Brad does not appear, try again without picking up anything along the way to the Station. (Don't worry about not getting your characters'signature weapon, as a shotgun can be found in the S.T.A.R.S. Office for Leon, and a Bow-Gun in the Cabin save area for Claire, so you don't have to worry about not picking them up in the begining when the shop-keeper dies.)

All Hung Up

While playing as Claire, if you equip the bow-gun and fire at a zombie that is in front of a wall, it will get pinned and die. This trick also works with crows, but it's not as effective as they are too fast to hit, but it can be done.

Vomiting Zombies

You will eventually become a little girl named Sherry in Claire's scenario. Walk up to a zombie and instead of biting you they will vomit.

Getting The Machine Gun

Play the first scenario and find the door with a small hand pad in the Umbrella Laboratory that requires two people to open. Even though you cannot get in, activate it anyway. Complete the first scenario and start the second. Find this pad again and activate it. The door will unlock and you can find a machine gun in the room.

Regaining The Precinct Key

If you discarded the Precinct Key, you can regain in the room where you put the Red Jewels into the statues. Search the crates on the left side of the statue to find the it. You can also find H. Gun Ammo and an Ink Ribbon in this room.

Defeating Tyrant

In the second scenario, after you put the joint plugs in, you will fight a evolved form of Tyrant. Use the following steps to easily defeat him. For Leon, run to the right from him as soon as the scene (with black lines at bottom and top) ends. Start shooting him with the custom magnum three times, then run toward the exit door. Ada Wong will appear and drop a special grenade launcher. Run towards the grenade launcher, pick it up and shoot one shot to kill the Tyrant. If you are not an expert, you will also need first aid sprays or herbs. For Claire, you will do the same thing only using the regular grenade launcher with acid rounds. After this Tyrant, you will open the gate and get on the train. Another intermission sequence will play. After it finishes, the train will stop. Run towards the back of the train until you see a tentacle drop down. Another intermission sequence will play, and you have to fight the last form of William Burkin, as a revolting blob. Run towards the front of the train until you reach the door. Stop and shoot him with the remaining rocket. Then, use the custom magnum or a grenade launcher with acid rounds. Shoot him until he melts. After that, go to where you started and watch the ending sequence. The "Tyrant" in the second scenario is a indeed a Tyrant of the T-00 series but his name is Mr. X.

Safe Code

The code for the safe in the room with the double blue doors is 4542.

Access To Secret Room

To get into the room with the fingerprint access, you must get the Red Umbrella Key card and go into the room with the bugs in it. Go to the computer and type in "GUEST" as a user name. It will take your fingerprint. Go to the fingerprint key pad and put your fingerprint in as the character being Leon or Claire and complete the game. Return to the fingerprint lock as the other character and do the same thing and you can go in. There are some Lickers in a glass container of liquid.